Two of my games, TRaiderII & TRaiderIII went unstable, the mouse would not control the program. Changed and checked everything to no avail. Then tried re-connecting the joystick port. All work after that. Contrary-wise one grandson's computer would not run some other game programs with the joystick connected!
I don't know what the logical connection between the mouse and joystick is.
Just passing along something to try to fix an ailing machine.